Summary of Reddit Comments on Pembrolizumab Side Effect Management

Keytruda (Pembrolizumab)

• Pros:
  • Effective in treating cancer: "Immunotherapy worked for my Dad. The cancer continued to shrink."
  • Manageable side effects: "Only side effect was the steroids would mess with his sugar."
• Cons:
  • Fatigue: "Fatigue is definitely a major side effect of keytruda."
  • Gastrointestinal issues: "Keep track of bowel movements, Keytruda can cause colitis if not monitored."
  • Weakness and recovery time: "Switching to 6-week treatment took a full day to recover."
• Cost: Varies by country, can be expensive in some regions.

Leronlimab

• Pros:
  • Potential for diverse applications: "Working in many different diseases as a standalone or in combination with other drugs."
  • Ongoing clinical trials for different conditions like COVID-19 pneumonia and cancer.
• Cons:
  • Side effects like diarrhea, fatigue, and pain: "My Dad used to vomit so much and had diarrhea and hemorrhoids... very painful."

General Observations

• Taking Time Off: Encouragement to take time off for mental health, even if side effects are mild.
• Positive Workplace Policies: Some employers offer paid time off for getting vaccinated.
• Support for Mental Health: Advocacy for taking breaks and using paid time off for self-care.

In conclusion, Keytruda has shown effectiveness in cancer treatment with manageable side effects, while Leronlimab is being tested for various conditions with some reported side effects. It's crucial to monitor and manage side effects, take necessary breaks for mental well-being, and consider the potential benefits and costs of treatments.